Yield of comparative genomic hybridization microarray in pediatric neurology practice

Leptospire genomic diversity revealed by microarray-based comparative genomic hybridization.

Comparative genomic hybridization was used to compare genetic diversity of five strains of Leptospira (Leptospira interrogans serovars Bratislava, Canicola, and Hebdomadis and Leptospira kirschneri serovars Cynopteri and Grippotyphosa). The array was designed based on two available sequenced Leptospira reference genomes, those of L. interrogans serovar Copenhageni and L. interrogans serovar Lai...

A survey of genomic diversity in Enterococcus faecalis by microarray based comparative 1 genomic hybridization 2

1 We have compared nine Enterococcus faecalis strains with E. faecalis V583 (V583), for 2 which a complete genome sequence and a genome-wide microarray is available. The strains 3 we have used in this study (the test strains) originated from various environments; 4 veterinarian, food, and environmental isolates, as well as lab strains. Comparative genomic 5 hybridization using microarrays (CGH)...

Extensive genomic diversity in pathogenic Escherichia coli and Shigella Strains revealed by comparative genomic hybridization microarray.

Escherichia coli, including the closely related genus Shigella, is a highly diverse species in terms of genome structure. Comparative genomic hybridization (CGH) microarray analysis was used to compare the gene content of E. coli K-12 with the gene contents of pathogenic strains. Missing genes in a pathogen were detected on a microarray slide spotted with 4,071 open reading frames (ORFs) of W31...

Comparative Genomic Hybridization (CGH)

High resolution genomic analysis of 18q- using oligo-microarray comparative genomic hybridization (aCGH).

The advent of oligonucleotide array comparative genomic hybridization (aCGH) has revolutionized diagnosis of chromosome abnormalities in the genetics clinic. This new technology also has valuable potential as a research tool to investigate larger genomic rearrangements that are typically diagnosed via routine karyotype. aCGH was used as a tool for the high-resolution analysis of chromosome cont...